當前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標記一抗 > bs-1447R-PEPE標記的缺氧誘導因子2α /EPAS1抗體
簡要描述:Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase ex
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